
The Story
Dulcosoft Oral Solution — No Longer Available in Ireland
⚠️ Dulcosoft has been discontinued and is no longer available in Ireland.
This has been confirmed by James Cloney MPSI, Co-Founder and Superintendent Pharmacist at Chemco Pharmacy, with over 20 years of pharmacy experience.
If you have been using Dulcosoft Oral Solution (macrogol) for constipation relief, you will need an alternative. Based on pharmacist review, Lactulose Fresenius 500ml is the recommended replacement — an established, widely used osmotic laxative available from Chemco Pharmacy without a prescription.
Shop Lactulose Fresenius 500ml — The Recommended Alternative →
Why Lactulose Fresenius is the Recommended Dulcosoft Alternative
Both Dulcosoft (macrogol) and Lactulose Fresenius are osmotic laxatives — they work by drawing water into the bowel to soften stool and relieve constipation. As James Cloney MPSI explains:
"Lactulose Fresenius is a well-established osmotic laxative that has been used in Irish pharmacy for decades. For patients who were using Dulcosoft for constipation relief, Lactulose Fresenius is the most appropriate readily available alternative — effective, gentle, and suitable for adults, children and older patients alike. It is available without a prescription from Chemco Pharmacy."
— James Cloney MPSI, Co-Founder & Superintendent Pharmacist, Chemco Pharmacy
Dulcosoft vs Lactulose — How They Compare
| Feature | Dulcosoft (macrogol) | Lactulose Fresenius |
|---|---|---|
| Active ingredient | Macrogol (polyethylene glycol) | Lactulose |
| Mechanism | Osmotic — draws water into bowel | Osmotic — draws water into bowel |
| Onset of action | 24–72 hours | 24–48 hours |
| Bloating/wind risk | Lower — not fermented by gut bacteria | Possible — fermented by gut bacteria |
| Suitable for children | Yes (aged 2+) | Yes (all ages) |
| Safe in pregnancy | Yes (with pharmacist guidance) | Yes (with pharmacist guidance) |
| Available in Ireland | No — discontinued | Yes — in stock at Chemco Pharmacy |
| Prescription required | No | No |
Shop Lactulose Fresenius 500ml Now →
Frequently Asked Questions
Is Dulcosoft still available in Ireland?
No. Dulcosoft Oral Solution has been discontinued and is no longer available in Ireland. This has been confirmed by James Cloney MPSI, Co-Founder and Superintendent Pharmacist at Chemco Pharmacy. If you have been prescribed or recommended Dulcosoft, speak with your pharmacist or GP about switching to an appropriate alternative.
What is the best alternative to Dulcosoft in Ireland?
Lactulose Fresenius 500ml is the pharmacist-recommended alternative to Dulcosoft for constipation relief in Ireland, as confirmed by James Cloney MPSI at Chemco Pharmacy. Both are osmotic laxatives that work by drawing water into the bowel to soften stool. Lactulose is well-established, effective, gentle and available without prescription. Order Lactulose Fresenius from Chemco Pharmacy here.
Is lactulose the same as macrogol?
They are different active ingredients but share the same mechanism — both are osmotic laxatives that draw water into the bowel. Macrogol (Dulcosoft's active ingredient) is not fermented by gut bacteria and tends to cause less bloating. Lactulose is fermented by gut bacteria which can cause some wind and bloating in sensitive individuals, particularly at higher doses. Both are effective for constipation relief. For most people, the difference in practice is small — if bloating is a concern, starting with a lower dose of lactulose and taking it with plenty of water minimises this effect.
Can I use lactulose instead of Dulcosoft for constipation?
Yes. Lactulose Fresenius is the pharmacist-recommended alternative for constipation relief now that Dulcosoft is no longer available in Ireland. It is available without prescription from Chemco Pharmacy. If you have any questions about switching from Dulcosoft to Lactulose, our pharmacy team — led by James Cloney MPSI — is available to advise.
Does my GP need to know Dulcosoft has been discontinued?
If Dulcosoft was on your prescription or part of a recommended treatment plan from your GP or hospital, it is worth informing them so they can update your records and prescribe an appropriate alternative. Your GP can prescribe lactulose on a medical card prescription in Ireland.

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Description
Dulcosoft Oral Solution — No Longer Available in Ireland
⚠️ Dulcosoft has been discontinued and is no longer available in Ireland.
This has been confirmed by James Cloney MPSI, Co-Founder and Superintendent Pharmacist at Chemco Pharmacy, with over 20 years of pharmacy experience.
If you have been using Dulcosoft Oral Solution (macrogol) for constipation relief, you will need an alternative. Based on pharmacist review, Lactulose Fresenius 500ml is the recommended replacement — an established, widely used osmotic laxative available from Chemco Pharmacy without a prescription.
Shop Lactulose Fresenius 500ml — The Recommended Alternative →
Why Lactulose Fresenius is the Recommended Dulcosoft Alternative
Both Dulcosoft (macrogol) and Lactulose Fresenius are osmotic laxatives — they work by drawing water into the bowel to soften stool and relieve constipation. As James Cloney MPSI explains:
"Lactulose Fresenius is a well-established osmotic laxative that has been used in Irish pharmacy for decades. For patients who were using Dulcosoft for constipation relief, Lactulose Fresenius is the most appropriate readily available alternative — effective, gentle, and suitable for adults, children and older patients alike. It is available without a prescription from Chemco Pharmacy."
— James Cloney MPSI, Co-Founder & Superintendent Pharmacist, Chemco Pharmacy
Dulcosoft vs Lactulose — How They Compare
| Feature | Dulcosoft (macrogol) | Lactulose Fresenius |
|---|---|---|
| Active ingredient | Macrogol (polyethylene glycol) | Lactulose |
| Mechanism | Osmotic — draws water into bowel | Osmotic — draws water into bowel |
| Onset of action | 24–72 hours | 24–48 hours |
| Bloating/wind risk | Lower — not fermented by gut bacteria | Possible — fermented by gut bacteria |
| Suitable for children | Yes (aged 2+) | Yes (all ages) |
| Safe in pregnancy | Yes (with pharmacist guidance) | Yes (with pharmacist guidance) |
| Available in Ireland | No — discontinued | Yes — in stock at Chemco Pharmacy |
| Prescription required | No | No |
Shop Lactulose Fresenius 500ml Now →
Frequently Asked Questions
Is Dulcosoft still available in Ireland?
No. Dulcosoft Oral Solution has been discontinued and is no longer available in Ireland. This has been confirmed by James Cloney MPSI, Co-Founder and Superintendent Pharmacist at Chemco Pharmacy. If you have been prescribed or recommended Dulcosoft, speak with your pharmacist or GP about switching to an appropriate alternative.
What is the best alternative to Dulcosoft in Ireland?
Lactulose Fresenius 500ml is the pharmacist-recommended alternative to Dulcosoft for constipation relief in Ireland, as confirmed by James Cloney MPSI at Chemco Pharmacy. Both are osmotic laxatives that work by drawing water into the bowel to soften stool. Lactulose is well-established, effective, gentle and available without prescription. Order Lactulose Fresenius from Chemco Pharmacy here.
Is lactulose the same as macrogol?
They are different active ingredients but share the same mechanism — both are osmotic laxatives that draw water into the bowel. Macrogol (Dulcosoft's active ingredient) is not fermented by gut bacteria and tends to cause less bloating. Lactulose is fermented by gut bacteria which can cause some wind and bloating in sensitive individuals, particularly at higher doses. Both are effective for constipation relief. For most people, the difference in practice is small — if bloating is a concern, starting with a lower dose of lactulose and taking it with plenty of water minimises this effect.
Can I use lactulose instead of Dulcosoft for constipation?
Yes. Lactulose Fresenius is the pharmacist-recommended alternative for constipation relief now that Dulcosoft is no longer available in Ireland. It is available without prescription from Chemco Pharmacy. If you have any questions about switching from Dulcosoft to Lactulose, our pharmacy team — led by James Cloney MPSI — is available to advise.
Does my GP need to know Dulcosoft has been discontinued?
If Dulcosoft was on your prescription or part of a recommended treatment plan from your GP or hospital, it is worth informing them so they can update your records and prescribe an appropriate alternative. Your GP can prescribe lactulose on a medical card prescription in Ireland.











